What kind of .22 are you using?? I do target practice with .22 rifles and don't use hearing protection because the human body makes louder noises without expelling anything. Not to be crude or anything.
I'm sorry I should have been more precise. When out doors with just my .22 I don't normally use hearing protection. But often I'm also shooting .40, .357, .38, etc. so I'm wearing it and don't take it off when I switch to my .22
However I also shoot indoors and a .22, unsuppressed can be pretty loud.
To the specifics of your question I have several .22 pistols and rifles. I've only used a suppressor indoors with the pistol.